2010-09-12 DOLPHINS AT BILLS

FINAL SCORE: 15 - 10

2010-09-19 BILLS AT PACKERS

FINAL SCORE: 7 - 34

2010-09-26 BILLS AT PATRIOTS

FINAL SCORE: 30 - 38

2010-10-03 JETS AT BILLS

FINAL SCORE: 38 - 14

2010-10-10 JAGUARS AT BILLS

FINAL SCORE: 36 - 26

2010-10-24 BILLS AT RAVENS

FINAL SCORE: 34 - 37

2010-10-31 BILLS AT CHIEFS

FINAL SCORE: 10 - 13

2010-11-07 BEARS AT BILLS

FINAL SCORE: 22 - 19

2010-11-14 LIONS AT BILLS

FINAL SCORE: 12 - 14

2010-11-21 BILLS AT BENGALS

FINAL SCORE: 49 - 31

2010-11-28 STEELERS AT BILLS

FINAL SCORE: 19 - 16

2010-12-05 BILLS AT VIKINGS

FINAL SCORE: 14 - 38

2010-12-12 BROWNS AT BILLS

FINAL SCORE: 6 - 13

2010-12-19 BILLS AT DOLPHINS

FINAL SCORE: 17 - 14

2010-12-26 PATRIOTS AT BILLS

FINAL SCORE: 34 - 3

2011-01-02 BILLS AT JETS

FINAL SCORE: 7 - 38